مطالعۀ عددی تنش حرارتی تابش لیزر روی بافت سالم و سرطانی پوست

نوع مقاله : مقاله پژوهشی

نویسندگان

گروه مهندسی مکانیک، دانشکده فنی و مهندسی، دانشگاه خوارزمی، تهران

چکیده

تولید حرارت در فرایند گرمادرمانی ناشی از لیزر ممکن است موجب آسیب‌دیدن بافت سالم شود. بنابراین، پیش‌بینی توزیع دما و بررسی امکان آسیب بافت در اثر افزایش دما، همواره اصلی مهم و ضروری به‌شمار می‌رود. در این پژوهش، تغییرات دمایی و تنش‌های حرارتی ناشی از حرارت لیزر روی یک بافت سالم و سرطانی پوست انسان، با استفاده از الگوریتم عددی مبتنی بر روش المان محدود مدل‌سازی ‌شده است. لازم به ذکر است، باریکه‌های لیزر به‌صورت گوسی در نظر گرفته شده و تضعیف نور لیزر در لایه‌های پوست مبتنی بر قانون بیر-لامبرت است و تغییر شکل در همۀ نقاط المان با معادلات تعادل بیان می‌شود. نتایج حل عددی شامل تأثیر شدت لیزر، شعاع تابش و طول موج بر توزیع دما، تنش فون مایسز و همچنین نقش پرفیوژن خون بر توزیع دما، ارائه می‌شود. همچنین، آسیب‌های حرارتی ناشی از لیزر بر روی بافت سرطانی، برمبنای تئوری آرنیوس ارزیابی می‌شود. نتایج می‌تواند به‌عنوان اطلاعات اولیه در اختیار پزشکان قرار گیرد و پیش‌بینی دقیقی از اتفاقات در حین درمان را در اختیار آن‌ها قرار دهد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Numerical Study on the Thermal Stress caused by Laser Radiation on Healthy and Cancerous Skin Tissue

نویسندگان [English]

  • Sajjad Davoodi
  • mostafa Esmaeili
  • Hassan Shokrollahi
Department of Mechanical Engineering, Faculty of Engineering, Kharazmi University, Tehran, Iran
چکیده [English]

The heat generation during laser-induced thermotherapy can damage healthy tissue. Therefore, it is necessary to predict the temperature distribution and the possibility of tissue damage due to temperature rise. In this study, temperature changes and thermal stresses caused by laser on a healthy and cancerous tissue of human skin are modeled using a numerical method based on the finite element technique. It should be noted that the laser beams are assumed to be Gaussian and the attenuation of the laser light in the skin layers is based on Beer-Lambert's law, and the deformation in all parts of the element is expressed by equilibrium equations. The numerical results include the effects of laser intensity, radiation radius and wavelength as well as the role of blood perfusion on the temperature and von Mises stress distributions. Laser thermal damage to cancerous tissue is also investigated based on Arrhenius' theory. The present results can provide as preliminary information to physicians and provide a detailed account of events during the treatment.

کلیدواژه‌ها [English]

  • Cancer‌ tissue
  • laser-induced thermotherapy
  • thermal stress
  • blood perfusion
  • thermal damage
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