استفاده مدل‌های اصطکاکی نوین به منظور بررسی خواص مکانیکی بافت سرطانی کبد

نوع مقاله : مقاله پژوهشی

نویسندگان

معین طاهری

زهرا سادات اقدامی

مهندسی مکانیک، دانشگاه اراک، اراک، ایران

10.22067/jacsm.2024.87206.1245

چکیده

امروزه سرطان کبد جابگاه ششم در میان سرطان ها و رتبه چهارم از علل مرگ و میر را به خود اختصاص داده است. بررسی وضعیت بدن و شناخت زودهنگام این بیماری می‌تواند در کنترل و درمان آن موثر باشد. بررسی خواص مکانیکی بافت کبد و مطالعه مدول یانگ آن موجب شناسایی وضعیت سلامت بافت و بیمار خواهد شد. در این پژوهش با استفاده از مدل‌های اصطکاکی دال، انتگرال‌گیری بازنشانی و مدل‌های بلیمن و سورین، به محاسبه مدول یانگ به صورت تئوری پرداخته شده است. همچنین با استفاده از میکروسکوپ نیروی اتمی این مدول به صورت تجربی استخراج شده است. مقایسه مدول‌های تئوری و تجربی به دست آمده، نتایجی نزدیک به هم خواهد داشت. با توجه به بررسی بافت و روابط در سطح نانو، مدل دوم بیلمن و سورین به دلیل کمتر بودن دامنه تغییرات و معادلات پیچیده تر، از دقت بالاتری برخوردار است. بنابراین استفاده از مدل دوم بیلمن و سورین در پژوهش‌های آتی پیشهاد می‌شود.

کلیدواژه‌ها

بافت سرطانی کبد

مدل اصطکاکی دال

انتگرال‌گیری بازنشانی

مدل‌های اصطکاکی بلیمن و سورین

میکروسکوپ نیروی اتمی

موضوعات

• مکانیک نانو ذرات

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عنوان مقاله English

Using new friction models to investigate the mechanical properties of liver cancer tissue

نویسندگان English

Moein Taheri

Zahra Sadat Eghdami

Mechanical Engineering, Arak University, Arak, Iran

چکیده English

Today, liver cancer ranks sixth among cancers and ranks fourth among the causes of death. Examining the condition of the body and early recognition of this disease can be effective in its control and treatment. Examining the mechanical properties of the liver tissue and studying its Young's modulus will identify the health status of the tissue and the patient. In this research, Young's modulus has been theoretically calculated using slab friction models, reset integration, and Bleiman and Sorin models. Also, using atomic force microscope, this modulus has been extracted experimentally. Comparison of theoretical and experimental modules obtained will have similar results. According to the examination of texture and relationships at the nano level, the second model of Billman and Sorin is more accurate due to the smaller range of changes and the more complex equation. Therefore, it is suggested to use the second model of Billman and Sorin in future researches.

کلیدواژه‌ها English

Liver cancer tissue

Dahl friction model

reset integration

Bleiman and Sorin friction models

atomic force microscope

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