Investigating the effect of different positions of the slot on performance of single-slot and double-slot coaxial antenna in the treatment of cancer in liver tissue by hyperthermia method
Numerical study of hyperthermia was performed using a microwave slot antenna in the treatment of liver cancer. The modeling of the problem in Comsol software is done symmetrically and two-dimensionally and the electromagnetic equation is coupled with the biothermal transfer equation. Temperature distribution, cancer tissue destruction, microwave absorption in liver tissue and specific absorption rate (SAR) are presented as results. The results showed that the two-hole antenna has a wider distribution of the amount of microwave absorbed than the single-slot antenna. The SAR distribution along the longitudinal axis of the antennas gradually increases and reaches its maximum point where the slot is located, and then the SAR distribution decreases rapidly and reaches its minimum at the end of the antenna. According to the results, changes in temperature in liver tissue also depend on the type of antenna and penetration depth, and temperature distribution and SAR distribution have a similar trend. Also, single-slot antenna is suitable for elliptical tumors and double-slot antenna is suitable for spherical tumors.
J. Prendergast, C. Lally, S. Daly, A. J. Reid, T. C. lee, D. Quinn, and F. Dolan, “Analysis of prolapse in cardiovascular stents: a constitutive equation for vascular tissue and finite-element modelling,” Journal of Biomechanical Engineering, vol. 125, no. 5, pp. 692-699, 2003. https://doi.org/10.1115/1.1613674
Mandrycky, Z. Wang, K. Kim, and D. H. Kim, “3D bioprinting for engineering complex tissues,” Biotechnology Advances, vol. 34, no. 4, pp. 422-434, 2016. https://doi.org/10.1016/j.biotechadv.2015.12.011
H. Lindner, and R. D. Issels, “Hyperthermia in soft tissue sarcoma,” Current Treatment Options in Oncology, vol. 12, no. 1, pp. 12-20, 2011. https://doi.org/10.1007/s11864-011-0144-6
M. Paulides, G. M. Verduijn, and N. V. Holthe, “Status quo and directions in deep head and neck hyperthermia,” Radiation Oncology, vol. 11, no. 21, pp. 1-14, 2016.https://doi.org/10.1186/s13014-016-0588-8
H. Pennes, “Analysis of tissue and arterial blood temperatures in the resting human forearm,” Journal of Applied Physiology, vol. 1, no. 2, pp. 93-122, 1948. https://doi.org/10.1152/jappl.1948.1.2.93
H. Almaki, R. Nasiri, A. Idris, M. Nasiri, F. A. A. Majid, and D. Losic, “Trastuzumab-decorated nanoparticles for in vitro and in vivo tumor-targeting hyperthermia of HER2+ breast cancer,” Journal of Materials `Chemistry B, vol. 5, no. 35, pp. 7369-7383, 2017. https://doi.org/10.1039/C7TB01305A
Liu, D. X. Zhao, H. Cui, L. Chen, Y. H. Bao, Y. Wang, and J. Y. Jiang, “Therapeutic hypothermia attenuates tissue damage and cytokine expression after traumatic brain injury by inhibiting necroptosis in the rat,” Scientific Reports, vol. 6, no. 24547, pp. 1-11, 2016. https://doi.org/10.1038/srep24547
Gas, “Transient Analysis of Interstitial Microwave Hyperthermia Using Multi-Slot Coaxial Antenna Analysis and Simulation of Electrical and Computer Systems,” Springer International Publishing, pp. 63-71, 2015. https://doi.org/10.1007/978-3-319-11248-0_5
haghighi, B., sadeghpour, H., & shafiey, M. (2023). Investigating the effect of different positions of the slot on performance of single-slot and double-slot coaxial antenna in the treatment of cancer in liver tissue by hyperthermia method. Journal Of Applied and Computational Sciences in Mechanics, 35(3), 17-32. doi: 10.22067/jacsm.2023.76281.1114
MLA
behrad haghighi; hadi sadeghpour; Mohammad shafiey. "Investigating the effect of different positions of the slot on performance of single-slot and double-slot coaxial antenna in the treatment of cancer in liver tissue by hyperthermia method", Journal Of Applied and Computational Sciences in Mechanics, 35, 3, 2023, 17-32. doi: 10.22067/jacsm.2023.76281.1114
HARVARD
haghighi, B., sadeghpour, H., shafiey, M. (2023). 'Investigating the effect of different positions of the slot on performance of single-slot and double-slot coaxial antenna in the treatment of cancer in liver tissue by hyperthermia method', Journal Of Applied and Computational Sciences in Mechanics, 35(3), pp. 17-32. doi: 10.22067/jacsm.2023.76281.1114
VANCOUVER
haghighi, B., sadeghpour, H., shafiey, M. Investigating the effect of different positions of the slot on performance of single-slot and double-slot coaxial antenna in the treatment of cancer in liver tissue by hyperthermia method. Journal Of Applied and Computational Sciences in Mechanics, 2023; 35(3): 17-32. doi: 10.22067/jacsm.2023.76281.1114
Send comment about this article